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Nicholas Dew teaches early modern European and Atlantic history. His interests are in the cultural history of France in the seventeenth and eighteenth centuries, particularly the connections between colonialism and science, technology and medicine. His first book, (Oxford University Press, 2009), maps the place of scholarly studies of Asia within the intellectual culture of France in the late seventeenth century. The book was awarded the Wallace K. Ferguson prize of the Canadian Historical Association in 2011.With James Delbourgo, he is the editor of聽 (Routledge, 2008), a collection of essays which began life as a workshop at UCLA's Clark Library. His current book project is a history of the trans-Atlantic dimensions of French science in the period 1670-1740.

Dew has held a SSHRC Standard Research Grant; a Dibner Fellowship in the History of Science and Technology at the Huntington Library; and an Inter-Americas Fellowship at the John Carter Brown Library at Brown University. Dew is a founding member (and former principal investigator) of the; and was a co-applicant in the SSHRC Strategic Knowledge Cluster "Situating Science"; as well as a Collaborator in the SSHRC Major Collaborative Research Initiative, "Making Publics". He has also been chair of the program in History and Philosophy of Science at 海角社区.

Along with Jean-Pierre Le Glaunec, he is co-editor of the 海角社区 Queen's University Press book series