Effects of Heparan sulfate acetyl-CoA: Alpha-glucosaminide N-acetyltransferase (HGSNAT) inactivation on the structure and function of epithelial and immune cells of the testis and epididymis and sperm parameters in adult mice.
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Published on: 29 Sep 2023
Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism.
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Published on: 18 Sep 2023
Helium is probably not the first thing that comes to mind for most people when they think about recycling 鈥� unless they鈥檙e experimental chemists working in 海角社区鈥檚 Nuclear Magnetic Resonance (NMR) facilities.
Published on: 16 Mar 2023
Victoria Glynn, the public program representative from GARM (Graduate Association of the Redpath Museum), has won the prestigious .
Published on: 13 Apr 2021
Office of Science Education Communications Assistant听Brent Jamsa听sat down with four students to discuss their upcoming presentations at the second annual Undergraduate Poster Showcase. This year, the highly-anticipated event will be hosted on March 16, 6-8 PM EST via Zoom. Register here to attend: .
Published on: 9 Mar 2021
There are currently three undergraduate research funding opportunities for Summer 2021: SURA, NSERC USRA, and Schull Yang International Experience Awards. These allow students to engage in a full-time summer research activity, and to gain research experience in an exciting academic setting, while receiving financial support.听 These are open to all B.Sc. and B.A. & Sc. students in the Faculty of Science. For Summer 2021, the Faculty of Science requires all project proposals to include a project the student can start and finish remotely.
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Published on: 19 Feb 2021
Glucose homeostasis and growth essentially depend on the hormone insulin engaging its receptor. Despite biochemical and structural advances, a fundamental contradiction has persisted in the current understanding of insulin ligand鈥搑eceptor interactions. While biochemistry predicts two distinct insulin binding sites, 1 and 2, recent structural analyses have resolved only site 1. Using a combined approach of cryo-EM and atomistic molecular dynamics simulation, we present the structure of the entire dimeric insulin receptor ectodomain saturated with four insulin molecules.
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Published on: 17 Feb 2020
By Cynthia Feng and Kira Smith
Office of Science Education team members Cynthia Feng and Kira Smith are working with members of the Science Undergraduate Society (SUS) on planning the next edition of the SUS鈥檚 highly anticipated Academia Week.
Published on: 9 Jan 2020
Reinhardt lab receives funding from the prestigious Marfan Foundation (USA) to explore the connection between diet and disease development in Marfan syndrome. Congratulations!
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Published on: 8 Oct 2019
TITLE:听Augmentation of cell numbers and function in the immune system by in vivo administration of North American (NA) ginseng (Panax Quinquefolium): Assessment in normal and cancer-bearing infant, juvenile, adult and elderly mice
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Published on: 7 Oct 2019
Title: Fibulin-4 exerts a dual role in LTBP-4L鈥搈ediated matrix assembly and function
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Published on: 30 Sep 2019
Amal Seffouh, a Postdoctoral Fellow in the Ortega lab, publishes her most recent work about the role of RbgA in the maturation of the 50S ribosomal subunit.
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Published on: 9 Sep 2019
Aida Razi鈥檚 last PhD thesis chapter now published online in the Nucleic Acids Research journal. This publication features the first cryo-EM structures obtained by the Ortega lab in the Titan Krios microscope at FEMR-海角社区.
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Published on: 4 Jul 2019
The telomerase holoenzyme responsible for maintaining telomeres in vertebrates requires many components in vivo, including dyskerin. Dyskerin binds and regulates the accumulation of the human telomerase RNA, hTR, as well as other non-coding RNAs that share the conserved H/ACA box motif. The precise mechanism by which dyskerin controls hTR levels is unknown, but is evidenced by defective hTR accumulation caused by substitutions in dyskerin, that are observed in the X-linked telomere biology disorder dyskeratosis congenita (X-DC).
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Published on: 23 Apr 2019
Reinhardt lab receives 5-year CIHR grant to investigate extracellular matrix-mediated regulation of microRNAs in health and disease. Congratulations!
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Published on: 24 Jan 2019
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