Alyson Elise Fournier, PhD
Alyson听Fournier's research focuses on the cellular and molecular mechanisms regulating axon degeneration and regeneration. Neurons in the central nervous system that are injured following traumatic injury or in neurodegenerative conditions fail to repair spontaneously. The abortive regenerative response can be attributed both to a failure of injured neurons to initiate a growth program and to the inhibitory growth environment. 听The aim of Fournier's research program is to develop a better understanding of the molecular signalling in neurons following traumatic injury or upon exposure to inflammatory insults such as those occurring in multiple sclerosis. Her current projects are focusing on the role of miRNAs and 14-3-3 adaptor proteins in neuronal responses to injury. A fuller understanding of the neuronal response to injury will be used to develop strategies to promote neuroprotection and neuronal regeneration.
Drake SS, Zaman A, Gianfelice C, Hua EM, Heale K, Afanasiev E, Klement W, Stratton JA, Prat A, Zandee S,听Fournier AE.听J Neuroinflammation. 2024 Nov 1;21(1):283. doi: 10.1186/s12974-024-03278-2.听PMID:听39487537听Free PMC article.
Hintermayer MA, Ju藕wik CA, Morquette B, Hua E, Zhang J, Drake S, Shi SS, Rambaldi I, Vangoor V, Pasterkamp J, Moore C,听Fournier AE.听J Neurosci. 2024 Oct 30;44(44):e1822232024. doi: 10.1523/JNEUROSCI.1822-23.2024.听PMID:听39266301
Groh AMR, Caporicci-Dinucci N, Afanasiev E, Bigotte M, Lu B, Gertsvolf J, Smith MD, Garton T, Callahan-Martin L, Allot A, Hatrock DJ, Mamane V, Drake S, Tai H, Ding J,听Fournier AE, Larochelle C, Calabresi PA, Stratton JA.听J Neurochem. 2024 Oct;168(10):3449-3466. doi: 10.1111/jnc.16120. Epub 2024 May 4.听PMID:听38702968
Drake SS, Mohammadnia A, Heale K, Groh AMR, Hua EM, Zaman A, Hintermayer MA, Zandee S, Gosselin D, Stratton JA, Sinclair DA,听Fournier AE.听bioRxiv [Preprint]. 2023 Oct 2:2023.09.30.560301. doi: 10.1101/2023.09.30.560301.PMID:听37873446听Free PMC article.听Preprint.
Drake SS, Zaman A, Simas T,听Fournier AE.听WIREs Mech Dis. 2023 Mar;15(2):e1594. doi: 10.1002/wsbm.1594. Epub 2023 Jan 4.听PMID:听36600404听Review.
